Children

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics. Golodirsen was tested in ambulatory patients with exon 53 skip amenable DMD. They
0 Comments
Many countries have implemented various nonpharmaceutical interventions (NPIs) such as social distancing mandates and lockdowns in response to the coronavirus disease 19 (COVID-19) pandemic. Although these measures reduced stress on the healthcare system in the absence of vaccines, they were associated with major socioeconomic costs. This led to a revival of the debate on whether
0 Comments
In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive. Journal in Which the Study was Published: Blood Cancer Discovery, a journal of the American
0 Comments
As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines’ potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago. Coronavirus vaccines may provide cross-protective immunity Northwestern Medicine
0 Comments
During the first 9 months of the COVID-19 pandemic, researchers did not find a significant difference in the number of new cancer diagnoses in Canadian children compared with before the pandemic, according to a study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210659. “Our findings suggest that among children in Canada, cancer diagnosis was not
0 Comments
Saliva samples are easy to obtain and useful for measuring antibodies to SARS-CoV-2 in children, which could facilitate epidemiological surveillance in school settings. The study, a collaboration between the Barcelona Institute for Global Health (ISGlobal), an institution supported by “la Caixa” Foundation, and the Hospital Sant Joan de Déu (HSJD), followed over 1,500 children who
0 Comments
A team of UK-based scientists has recently evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in preventing household transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in England. Their findings indicate that the vaccines effectively reduce transmission of SARS-CoV-2 alpha and delta variants from breakthrough infections in the household setting, despite having reduced
0 Comments
Multisystem inflammatory syndrome (MIS) is a new systemic inflammatory acute onset disease that mainly affects children (MIS-C) and, at a lesser frequency, adults. The disease usually occurs in children 3-6 weeks after acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Study: Autoantibody Release in Children after Corona Virus mRNA Vaccination: A Risk Factor of
0 Comments
Researchers at Yale University analyzing specialized MRI exams found significant changes in the microstructure of the brain’s white matter in adolescents and young adults with autism spectrum disorder (ASD) compared to a control group, according to research being presented next week at the annual meeting of the Radiological Society of North America (RSNA). The changes
0 Comments
Quarraisha Abdool Karim has spent the past three decades studying HIV and AIDS. She has become one of the world’s leading epidemiologists and made major contributions to the global understanding of how HIV affects young women. As associate scientific director of the Centre for the AIDS Programme of Research in South Africa (CAPRISA), Abdool Karim
0 Comments
The perception of gender in children’s voices is of special interest to researchers, because voices of young boys and girls are very similar before the age of puberty. Adult male and female voices are often quite different acoustically, making gender identification fairly easy. Gender perception is much more complicated in children because gender differences in
0 Comments
Cynthia Rogers, MD, visits a baby in the Newborn Intensive Care Unit at St. Louis Children’s Hospital. Rogers is helping lead a national study aimed at understanding how prenatal factors and early life experiences influence brain development and behavior in infants and young children. Researchers at Washington University School of Medicine in St. Louis are
0 Comments
A new study summarized in a research letter published in JAMA Pediatrics reveals that a number of factors, including negative impacts from the pandemic during pregnancy, health care experiences, and reports of discrimination, made it less likely that infants received their recommended vaccinations in the first months of their lives. Led by Heidi Preis, MSW,
0 Comments
Washington University in St. Louis is joining a major international effort to advance data science, catalyze innovation and spur health discoveries across Africa. Researchers at the School of Medicine are receiving one of 19 grant awards that will support data science research and training activities in Africa. The researchers will focus their efforts on developing
0 Comments
Weill Cornell Medicine has received a $1.27 million grant from the United States Department of Defense (DoD) to develop treatment for a rare but devastating eye condition largely affecting military personnel who suffer traumatic eye injuries in combat. Under the three-year grant, investigators will test the safety and effectiveness of two newly developed antibodies to
0 Comments
Researchers from the University of Eastern Finland, the University of Exeter, and the University of Bristol carried out the study using data from one of the world’s most extensive ongoing prospective birth cohort studies – the Avon Longitudinal Study of Parents and Children (ALSPAC). Atherosclerotic traits referred to as arterial stiffness seem to independently cause
0 Comments
Researchers have compiled the most comprehensive road map of the protein composition of human lungs, providing a clearer picture of the healthy development of this essential organ that made terrestrial life possible. The study, led by scientists at the Department of Energy’s Pacific Northwest National Laboratory, describes how thousands of molecules are modulated in a
0 Comments
The coronavirus disease 2019 (COVID-19) outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a sharp rise in deaths and the number of infections worldwide. The pandemic has resulted in the deaths of more than 5.1 million people from more than 254 million infections as of November 18, 2021. Therefore,
0 Comments
Valsartan, an angiotensin II receptor blocker drug, delayed disease progression and improved cardiac structure and function in patients with early-stage hypertrophic cardiomyopathy, according to results from a recent clinical trial published in Nature Medicine. This is the first time we have identified a treatment that may actually impact the underlying disease process, as opposed to
0 Comments