Clinical Trials & Research

Mar 8 2021 Antibiotic-resistant bacteria have become a global threat today, owing in part to the efficiency with which resistance spreads among them. Some of this spread happens in waterbodies—and our wastewater systems are no exception. A group of scientists from Korea and the US has now conducted some of the groundwork needed to optimize
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Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions — an essential, but increasingly transient job in executing treatment-advancing clinical trials, Vanderbilt University Medical Center researchers found. Danielle Buchanan, BS, clinical translational research coordinator III in the Department of Neurology, and Daniel Claassen, MD, MS, chief of
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Sponsored Content by PittconMar 4 2021 Thought LeadersDaniel W. Armstrong Welch Distinguished Professor, Dept. ChemistryIn this interview, Dr. Daniel Armstrong from the University of Texas at Arlington talks to News-Medical Life Sciences about his upcoming Pittcon presentation. Could you start by telling us what D-amino acids are and what role they have in a healthy
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CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip, today announced it has received a grant from Innovate UK, the UK’s innovation agency, to develop human-relevant MPS to advance investigations into SARS-CoV-2 infection. Image Credit: CN Bio The funding will be used to develop and test advanced cell
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Thought LeadersDr. Mahshid DehghanInvestigator, Nutrition Epidemiology ProgramMcMaster University In this interview, News-Medical speaks to Dr. Mahshid Dehghan about her latest research into diet, and how a diet high in carbohydrates could increase your risk of heart disease. What provoked your research into diets? Diet is one of the most important modifiable risk factors for cardiovascular
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A University of Texas at Arlington researcher has received an Office of Naval Research (ONR) grant to examine the mechanics of how blast-like events cause damage to the brain. Ashfaq Adnan, professor of mechanical and aerospace engineering, has received a three-year, $944,845 grant to study the potential link between blast-like trauma and cellular and tissue
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Promising new research shows aerobic exercise may help slow memory loss for older adults living with Alzheimer’s dementia. ASU Edson College of Nursing and Health Innovation Professor Fang Yu led a pilot randomized control trial that included 96 older adults living with mild to moderate Alzheimer’s dementia. Participants were randomized to either a cycling (stationary
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Feb 26 2021 Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies, and consumer health products, and Delphi Genetics, a plasmid DNA (pDNA) cell and gene therapy contract development and manufacturing organization (CDMO) based in Gosselies, Belgium, today announced that they have entered into
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Food products are one of the most traded commodities worldwide. With each passing year, the global food supply chain will continue to support the growing population worldwide. Due to such megatrends, food safety regulations are immensely important. Absence of food safety regulations can lead to undetected food allergens and contaminants that may lead to foodborne
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The second study published in as many months has identified another reason to add more mushrooms to the recommended American diet. The new research, published in Food & Nutrition Research (February 2021), examined the addition of mushrooms to U.S. Department of Agriculture (USDA) Food Patterns resulting in the increase of several micronutrients including shortfall nutrients
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As the world continues to seek solutions in response to the coronavirus pandemic, Beckman Coulter Life Sciences announces it is the first United States distributor of the Genedrive® 96 SARS-CoV-2 kit. The agreement with the near-patient molecular diagnostics company, genedrive plc (LSE: GDR), is for distribution in the US and throughout Europe. The Genedrive® 96
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Thought LeadersProfessor Robert BraggProfessorUniversity of the Free State News-Medical speaks to Professor Robert Bragg about disinfectants and how they could be helping bacteria to become resistant. What provoked your research into bacteria and their resistance? I have been involved in research on the control of animal diseases for many years now. The control of any
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Disorders of the cells’ energy supply can cause a number of serious diseases, but also seem to be connected to aging. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit
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With the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, the coronavirus disease 2019 (COVID-19) pandemic began. In just over a year, the virus has caused over 109 hundred million documented infections and taken more than 2.4 million lives. A new preprint on the bioRxiv* server describes the development of a
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The emergence of the novel coronavirus disease (COVID-19) was first reported in Wuhan, China, in December 2019 and its rapid spread across the world has caused the World Health Organization (WHO) to announced a Public Health Emergency of International Concern (PHEIC). COVID-19’s causative pathogen – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – is highly
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Feb 18 2021 For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another. Individual transporter particles captured by the cryo-EM (left), the structure solved by averaging thousands of
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Findings from a new Geisel-led study, published in the Journal of General Internal Medicine, reveal that there is substantial variation across different regions of the country in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, and that areas with greater use of these prescription drugs experience higher hip fracture rates. In
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The immune response to infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the ongoing coronavirus disease 2019 (COVID-19), consists of both humoral and cellular responses. Serum antibodies against the virus neutralize it by preventing its entry into the cell and the successful establishment of infection. Other antibodies help to clear
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Researchers of the Research Programme on Biomedical Informatics (GRIB) from UPF and Hospital del Mar Medical Research Institute (IMIM) in Barcelona, Spain, have identified behavioural and linguistic changes in tweets in Spanish published by users suffering from depression and who are taking medication to treat this disease. Their work has been published in Journal of
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Novel genetic associations could pave the way for early interventions and personalized treatment of an incurable condition. Scientists from the University of Bergen (Norway) and Karolinska Institutet (Sweden) have discovered the genes involved in autoimmune Addison’s disease, a condition where the body’s immune systems destroys the adrenal cortex leading to a life-threatening hormonal deficiency of
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Using publicly available coronavirus disease 2019 (COVID-19) data from Israel, a study suggests the BioNTech-Pfizer BNT162b2 vaccine is proving highly effective in the real world. Several vaccines have now been approved for COVID-19, and many countries have started intensive vaccination programs. In Israel, vaccination started on December 20, 2020. By the end of January, 33%
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Feb 12 2021 An Australian-first plan to boost primary care research and drive improved patient outcomes, has been backed by $1 million in grant funding. The RACGP, together with TROPHI partners – the Monash University Department of General Practice and the University of Melbourne Department of General Practice – have welcomed the grant from the
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New research from Trinity College Dublin suggests that older adults can be more focused, less impeded by anxiety and less mentally restless than younger adults. The team at the Trinity College Institute of Neuroscience (TCIN) (today, Wednesday, 10th February 2021) show that older adults appear to mitigate the negative aspects of cognitive decline by increasing
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Clostridioides difficile infection (rCDI) occurs in the gut and is caused by the Gram-positive, spore-forming anaerobic bacterium, C. difficile when its spores attach to fecal matter and are transferred from hand to mouth by health care workers. Patients undergoing antibiotic treatment are especially susceptible as the microorganisms that maintain a healthy gut are greatly damaged
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Tecan and laboratory software specialist UgenTec have announced a collaboration to develop fully integrated, sample-to-result solutions for PCR workflows. This newly formed partnership will combine Tecan’s liquid handling and automation expertise with UgenTec’s best-in-class FastFinder software, integrating end-to-end automation with comprehensive data analysis and workflow tools, providing high throughput solutions for molecular testing. The COVID-19
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