Clinical Trials & Research

One of the immune system’s oldest branches, called complement, may be influencing the severity of COVID disease, according to a new study from researchers at Columbia University Irving Medical Center. Among other findings linking complement to COVID, the researchers found that people with age-related macular degeneration — a disorder caused by overactive complement — are
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Reviewed by Emily Henderson, B.Sc.Aug 1 2020 The Emergency Committee on COVID-19, convened by the WHO Director-General under the International Health Regulations (2005) (IHR), held its fourth meeting on 31 July. In its statement following the meeting, published today, it expressed “appreciation for WHO and partners’ COVID-19 pandemic response efforts, and highlighted the anticipated lengthy
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Jul 31 2020 Promega Corporation has surpassed all its environmental improvement goals set for the end of 2020, and achieved absolute reductions in key sustainability metrics, according to the company’s newly released Corporate Responsibility Report. The annual report details the global biotech manufacturer’s outcomes from the previous year in the areas of employee well-being, community
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Jul 29 2020 A world-leading University of Waterloo spinoff company, that decodes blood samples for potential treatments for illnesses like cancer and COVID-19, is expanding operations with the help of a $5-million USD investment. Bin Ma, a University of Waterloo computer science professor who co-founded Rapid Novor in 2015, says the company’s technology is the
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Interview conducted by Emily Henderson, B.Sc.Jul 28 2020 Thought LeadersDr. Robert M. SargisAssociate Professor of MedicineDivision of Endocrinology, Diabetes and Metabolism News-Medical speaks to Dr. Robert M. Sargis about his research into whether medication is exposing us to hormone-disrupting chemicals. What led you to begin this research? We have been studying endocrine-disrupting chemicals for many
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According to new research published in the preprint server medRxiv* in July 2020, the use of hydroxychloroquine (HCQ) among outpatients in clinical trials, without high-risk factors for cardiac arrhythmia, is safe, with gastrointestinal side-effects being the most common side effects and no fatal adverse outcomes. As the COVID-19 pandemic continues all around the world, with
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Jul 24 2020 A research group from the Scripps Research Institute in Jupiter, US, has shown that the hydroxychloroquine drug interferes with only one of two somewhat redundant pathways that activate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) to mediate the infectious process. Their paper is currently available on the bioRxiv* preprint
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Even as the COVID-19 pandemic continues to spread over the world, causing over 600,000 deaths in less than seven months, scientists continue to seek the reasons for the difference in disease severity from person to person. Many patients with COVID-19 develop fatal acute respiratory distress syndrome, with an exaggerated inflammatory immune response in the lungs.
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Jul 20 2020 Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, and Heriot-Watt University, a specialist, pioneering Scottish University, today announced they have been awarded a Knowledge Transfer Partnership (KTP) grant from Innovate UK, the UK’s innovation agency. The grant will facilitate the development of novel droplet generator
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Reviewed by Emily Henderson, B.Sc.Jul 17 2020 Scientists at Fox Chase Cancer Center and Ben-Gurion University of the Negev (BGU) have received a new grant from the United States-Israel Binational Science Foundation (BSF) that will fund continuing research on an antibody developed as part of a longstanding collaboration between the two organizations. The research focus
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Widespread use of pesticides and other agrochemicals can speed the transmission of the debilitating disease schistosomiasis, while also upsetting the ecological balances in aquatic environments that prevent infections, finds a new study led by researchers at the University of California, Berkeley. Schistosomiasis, also known as snail fever, is caused by parasitic worms that develop and
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A prominent Australian pharmacologist has called for a new approach to treating COVID-19 as hopes fade of finding an effective vaccine or antiviral before the end of the year. University of South Australia (UniSA) Emeritus Professor Richard Head says scientists should be focusing on repurposing existing proven drugs to block the acute inflammatory responses to
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Abdominal weight gain, which is common during the postmenopause period, is associated with an array of health problems, including diabetes and heart disease. A new study suggests that the use of antidepressants, beta-blockers, and insulin during the menopause transition is partially to blame for such unhealthy weight gain. Study results are published online today in
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The standard diagnostic test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the reverse transcriptase-polymerase chain reaction (RT-PCR) assay. Now, a new study published on the preprint server medRxiv* in July 2020 describes the use of saliva as a sample in RT-PCR for diagnosis in place of nasopharyngeal or oropharyngeal swabs. The Need
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Strategies for the safe reopening of low and middle-income countries (LMICs) from months of strict social distancing in response to the ongoing COVID-19 pandemic must recognize that preserving people’s health is as important as reviving the economy, argue an international team of researchers. The team also say that strategies need to be based on local
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Acute ischemic strokes (AIS) associated with COVID-19 are more severe, lead to worse functional outcomes and are associated with higher mortality , according to new research published yesterday in Stroke, a journal of the American Stroke Association, a division of the American Heart Association. In “Characteristics and Outcomes in Patients with COVID-19 and Acute Ischemic
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Group of biomedical engineers from biotech company Gruppo Fos Lithuania together with researchers at Kaunas University of Technology and Lithuanian University of Health Sciences have patented technology for advanced health monitoring of stroke survivors. It is the first solution in the world which monitors and analyses simultaneously a patient’s health parameters from the affected part
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Jul 8 2020 The British Society of Gastroenterology (BSG) has issued interim guidance, pending the publication of its new Coeliac Guidelines in 2021, so that some adults with suspected coeliac disease can now be diagnosed based on blood test results alone, cutting out the long wait for an endoscopy with biopsy. Diagnosis of coeliac disease
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