Clinical Trials & Research

Reviewed by Emily Henderson, B.Sc.Nov 24 2020 A team from the Institut national de la recherche scientifique (INRS) has demonstrated the effectiveness of an inexpensive molecule to fight antibiotic-resistant strains of the bacteria responsible for gonorrhea and meningococcal meningitis. These two infections affect millions of people worldwide. The results of this research, led by Professor
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Non-pharmaceutical interventions (NPIs) are currently holding the fort against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),  the causative agent for the coronavirus disease 2019 (COVID-19) pandemic. A few NPIs that have been adopted globally are travel restrictions, social distancing, and personal protective measures. Currently, successful treatments for COVID-19 disease, or effective vaccines against SARS-CoV-2,
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Reviewed by Emily Henderson, B.Sc.Nov 20 2020 Simple, non-invasive imaging at the point of care can aid the diagnosis of corneal infections, reducing the risk of sight loss and helping patients’ vision return to pre-infection levels. Bacterial keratitis is one of the most common corneal infections in the western world, often caused by contaminated contact
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The COVID-19 pandemic has caused a massive health, socio-economic, and financial crisis across the world. Without a preventive or curative solution against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it will continue to impact public health and life globally. Despite this, COVID-19 is often downplayed to be only a seasonal flu by many. This may
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Reviewed by Emily Henderson, B.Sc.Nov 18 2020 University of Cincinnati pharmaceutical sciences researcher Bingfang Yan, DVM, has received a $443,000 grant from the National Institutes of Health to study how common medicines against viral infections are genetically impacted for therapeutic effectiveness and safety through metabolic conversions in the body. The two medicines being studied are
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A new study conducted by researchers at RWTH Aachen University in Germany has found no evidence to support the hypothesis that severe outcomes in cases of coronavirus disease 2019 (COVID-19) may be linked to accelerated biological aging. As a person ages, specific DNA methylation changes occur in the genome that can be combined into “epigenetic
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As the coronavirus disease (COVID-19) pandemic continues to spread globally, more information about the virus and disease process unravels. It is well established that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the body through cellular gateways, the angiotensin-converting enzyme 2 (ACE2). Now, a team of scientists revealed that dopamine-release mechanisms in the brain
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Nov 12 2020 MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus’s ability to replicate itself and stimulate the host cell’s inflammation response. If researchers could devise ways to block
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Nov 13 2020 Porvair Sciences reports, due to promising results, it has agreed with its collaborative partners to make additional investment in the CEAT project** which aims to dramatically improve the diagnosis and treatment of ovarian cancer. In the initial stage of the CEAT (Cluster for Epigenomic and Antibody Drug Conjugate Therapeutics) project – Porvair
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Nov 12 2020 Dotmatics Ltd, a scientific informatics software and services company that is driving the automation of laboratory data workflows for scientific discovery and innovation research, today announced a new partnership with LabVoice to provide R&D scientists with the ability to record, access, and track data within an electronic laboratory notebook (ELN) using hands-free
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Researchers have found that nafamostat mesylate, when injected in the nasal cavity of Syrian hamsters, can decrease initial SARS-CoV-2 viral loads in their nose. However, this effect was temporary and further testing is required to determine clinically significant effects. The research group’s findings are available on the preprint server bioRxiv*. The severe acute respiratory syndrome
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Reviewed by Emily Henderson, B.Sc.Nov 10 2020 Northern Arizona University researcher Jeff Foster is leading an international effort to study and track the spread of one of the most important infectious diseases in humans and livestock worldwide. Brucellosis infects an estimated 500,000 people and millions of animals each year – cattle, pigs, sheep, goats –
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Most of the vaccine research in the current coronavirus disease 2019 (COVID-19) pandemic has focused on the role of the angiotensin-converting enzyme 2 (ACE2) receptor in mediating viral entry into the host cell. However, a recent study published on the preprint server bioRxiv* in November 2020 uncovers the major role played by the N-terminal domain
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Reviewed by Emily Henderson, B.Sc.Nov 6 2020 A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity. Research published today in the journal PLosMed investigates the impact of high glucose in mothers with gestational diabetes mellitus (GDM) and changes to infants
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Reviewed by Emily Henderson, B.Sc.Nov 6 2020 A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 that is required for their entry into hepatocytes. These findings, published today in the scientific journal Nature Communications, open
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Reviewed by Emily Henderson, B.Sc.Nov 5 2020 In states that have expanded Medicaid availability as part of the Affordable Care Act (ACA), mortality rates for three major forms of cancer are significantly lower than in states that have not expanded their Medicaid, a new study by researchers at Dana-Farber Cancer Institute, Brigham and Women’s Hospital,
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Reviewed by Emily Henderson, B.Sc.Nov 2 2020 The risk of subsequent fecal incontinence and intestinal gas leakage is significantly higher among women who, during childbirth, have suffered a sphincter injury and consequent damage to the anal sphincter muscle, was shown in a new study from the University of Gothenburg. Most births in Sweden occur without
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Reviewed by Emily Henderson, B.Sc.Oct 30 2020 Specialists from the Department of Fundamental Medicine of Far Eastern Federal University (FEFU) with Russian and Japanese colleagues have probed into mechanisms of COVID-19 inside-the-body distribution linked to erythrocytes damaging. According to researchers, the virus might attack red marrow, thus being detrimental not only for erythrocytes in the
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Reviewed by Emily Henderson, B.Sc.Oct 30 2020 The same biochemical triggers that spur a “fight or flight” response when we encounter threats may help tumor cells to thrive. A team of researchers from Roswell Park Comprehensive Cancer Center is looking at ways to disrupt that dynamic so that cancer treatments can be more effective. Their
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Reviewed by Emily Henderson, B.Sc.Oct 30 2020 Both cancer patients and their medical teams found it beneficial when patients shared their symptoms in real time using a web- or telephone-based reporting system, according to a national multi-institutional study. Ethan Basch, MD, MSc, at the University of North Carolina Lineberger Comprehensive Cancer Center, and his colleagues
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Reviewed by Emily Henderson, B.Sc.Oct 29 2020 A viral Facebook post claims that former President Barack Obama’s health insurance law penalized a family a large amount of money for not buying health insurance and that President Donald Trump was responsible for stopping the practice. This story was produced in partnership with PolitiFact.It can be republished
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Reviewed by Emily Henderson, B.Sc.Oct 28 2020 Teen-age boys exposed to pro-cannabis advertising and social media posts are more likely than female peers to associate marijuana use with improving sexual activity, new research from Washington State University suggests. Researchers found that the adolescent males expected cannabis users to be less inhibited and enjoy sex more,
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